Chapter 5 Section 4: Proteins and their cellular locations, after p. 185:
Topic Name: Protein G at Carnegie Mellon University
Go to this web site showing the structure of Protein G. As always with the structure viewing software plug-in Chime, you can click on the structure and move it around. Click on the X box labeled "alpha-Helix, only." Wait and watch as the structure of the helix is depicted first in the stick diagram showing the individual amino acid structures. Then the structural representation changes to the backbone of the helix, and then to the shorthand ribbon diagram.
Click on the X box labeled “beta-Sheet, only.” Again wait for the structural representations to show first the amino acids, then the backbone of the polypeptide alone, and finally the ribbon diagram.
Click to see the hydrophobic amino acid side chains.
Click to see the hydrophilic side chains.
How many alpha-helices and beta-sheets does Protein G contain?
What connects the alpha-helices and beta-sheets?
Describe the 3-dimensional structure of an alpha-helix. Of a beta-sheet. How are they different?
Where do the hydrophilic side chains point?
Where do the hydrophobic side chains point?